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Aspirin and hydrocodone

Pronunciation:  AS pir in/hye droe KOE done
Generic:  aspirin-hydrocodone
Brand:  Alor 5/500, Azdone, Damason-P, Lortab ASA, Panasal 5/500.

What is aspirin and hydrocodone?

Hydrocodone (related to codeine) is in a class of drugs called narcotic analgesics. It is a pain reliever. Aspirin is also a pain reliever, as well as an anti-inflammatory and a fever reducer. Aspirin increases the effects of hydrocodone.

Together, aspirin and hydrocodone, are used to treat moderate-to-severe pain.

Aspirin and hydrocodone may also be used for purposes other than those listed in this medication guide.

How should I take aspirin and hydrocodone?

Take aspirin and hydrocodone exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Aspirin and hydrocodone can be taken with food or milk if it causes stomach upset.

Do not take more of this medication than is prescribed. If the pain is not being adequately treated, talk to your doctor.

Do not stop taking aspirin and hydrocodone suddenly if you have been taking it continuously for more than 5 to 7 days. Stopping suddenly could cause withdrawal symptoms and make you uncomfortable. Your doctor may want to gradually reduce the dose.

Constipation may be a side effect of treatment with aspirin and hydrocodone. Increasing the amount of fiber and water (six to eight full glasses) in the diet may reduce constipation.

Do not share this medication with anyone else.

Store aspirin and hydrocodone at room temperature away from moisture and heat.

What are the possible side effects of aspirin and hydrocodone?

If you experience any of the following serious side effects, stop taking aspirin and hydrocodone and seek emergency medical attention or contact your doctor:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • slow, weak breathing;
  • seizures;
  • cold, clammy skin;
  • severe weakness or dizziness;
  • unconsciousness; or
  • black, bloody, or tarry stools or blood in urine or vomit.

Other, less serious side effects may be more likely to occur. Continue to take aspirin and hydrocodone and talk to your doctor if you experience

  • constipation;
  • dry mouth, nausea, vomiting, or decreased appetite;
  • dizziness, tiredness, or lightheadedness;
  • muscle twitches;
  • sweating;
  • itching or rash;
  • decreased urination;
  • decreased sex drive; or
  • ringing in the ears.

Aspirin and hydrocodone is habit forming. Do not stop taking it suddenly.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect aspirin and hydrocodone?

Do not take aspirin and hydrocodone if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. Dangerous side effects could result.

Drowsiness or dizziness caused by aspirin and hydrocodone may be increased by other drugs such as antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), other pain relievers, anxiety medicines, and muscle relaxants. Together, these medicines may cause dangerous sedation, possibly resulting in unconsciousness or death. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.

Do not take other over-the-counter and prescription products that contain aspirin. Too much aspirin could be dangerous. Talk to your doctor or pharmacist before taking any over-the-counter preparations.

Drugs other than those listed here may also interact with aspirin and hydrocodone. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

What should I avoid while taking aspirin and hydrocodone?

Avoid alcohol while taking aspirin and hydrocodone. Alcohol can greatly increase drowsiness and dizziness caused by the medication which could be dangerous. Also, alcohol increases the risk of stomach bleeding when taking aspirin.

Use caution when driving, operating machinery, or performing other hazardous activities. Hydrocodone may cause drowsiness. If you experience drowsiness, avoid these activities.

Do not take other over-the-counter and prescription products that contain aspirin. Too much aspirin could be dangerous. Talk to your doctor or pharmacist before taking any over-the-counter preparations.

Drowsiness or dizziness caused by aspirin and hydrocodone may be increased by other drugs such as antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), other pain relievers, anxiety medicines, and muscle relaxants. Together, these medicines may cause dangerous sedation, possibly resulting in unconsciousness or death. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of an aspirin and hydrocodone overdose include slow breathing, seizures, dizziness, weakness, loss of consciousness, coma, confusion, tiredness, cold and clammy skin, ringing in the ears, and small pupils.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Do not take a double dose of this medication. Wait the prescribed amount of time before taking the next dose.

What is the most important information I should know about aspirin and hydrocodone?

Do not stop taking aspirin and hydrocodone suddenly if you have been taking it continuously for more than 5 to 7 days. Stopping suddenly could cause withdrawal symptoms and make you uncomfortable. Your doctor may want to gradually reduce the dose.

Avoid alcohol while taking aspirin and hydrocodone. Alcohol can greatly increase drowsiness and dizziness caused by the medication which could be dangerous. Also, alcohol increases the risk of stomach bleeding when taking aspirin.

Do not take more of this medication than is prescribed. If the pain is not being adequately treated, talk to your doctor.

Do not take other over-the-counter and prescription products that contain aspirin. Too much aspirin could be dangerous. Talk to your doctor or pharmacist before taking any over-the-counter preparations.

Drowsiness or dizziness caused by aspirin and hydrocodone may be increased by other drugs such as antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), other pain relievers, anxiety medicines, and muscle relaxants. Together, these medicines may cause dangerous sedation, possibly resulting in unconsciousness or death. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.

What should I discuss with my healthcare provider before taking aspirin and hydrocodone?

Before taking this medication, tell your doctor if you have

  • a bleeding or blood clotting disorder;
  • a stomach ulcer;
  • asthma;
  • urinary retention;
  • an enlarged prostate;
  • hypothyroidism;
  • seizures or epilepsy;
  • gallbladder disease;
  • a head injury;
  • Addisons disease; or
  • a history of drug or alcohol addiction.

You may not be able to take aspirin and hydrocodone, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Hydrocodone may cause addiction and withdrawal symptoms as well as other harmful effects in an unborn baby. Do not take aspirin and hydrocodone without first talking to your doctor if you are pregnant or could become pregnant during treatment.

Hydrocodone may also cause addiction and withdrawal symptoms in a nursing baby. Do not take aspirin and hydrocodone without first talking to your doctor if you are breast-feeding a baby.

If you are older than 60 years of age, you may be more likely to experience side effects from aspirin and hydrocodone. Your doctor may prescribe a lower dose of the medication.

Do not use any medication that contains aspirin to treat a child or teenager who has a fever, flu symptoms, or chicken pox without first talking to a doctor. In children younger than 18 years of age, aspirin may increase the risk of Reye's syndrome, a rare but often fatal condition.

Where can I get more information?

Your pharmacist has additional information about aspirin and hydrocodone written for health professionals that you may read.

What does my medication look like?

Aspirin and hydrocodone is available with a prescription under the brand names Azdone and Lortab. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Aspirin/hydrocodone strengths are as follows:

  • Azdone 500 mg/5 mgflat, truncated, bisected, mottled-pink tablets
  • Lortab ASA 500 mg/ 5 mgcapsule-shaped, mottled-pink tablets

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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